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CBD Bioavailability

CBD Bioavailability

Whether you are a new user or an experienced one, everyone wants to know and understand how to get the most effective results with the CBD products they take. One of the most important things to understand when thinking about this is CBD Bioavailability.

What is CBD Bioavailability?

CBD is available in many including topicals, tinctures, oils, vape liquids, gummies, capsules and more. Each of these products utilizes a different delivery method. Each type of product also comes in different dosages and MG strengths.

All the different options can be very confusing. You may want to try CBD, but which method should you use and how much CBD should you take? These questions can best be answered by understanding what bioavailability means.

Bioavailability is the degree and rate at which CBD is absorbed into the bloodstream. Bioavailability determines how much CBD is actually present to provide your desired level of effect. Bioavailability varies based on the method of consumption and concentration of CBD in the product.

What’s the best way to take CBD?

To get the best CBD bioavailability out of your product, the most direct route would be by IV which means you would need to inject it directly into your bloodstream. This method delivers 100% of the CBD you take but is not at all convenient for most people.

Oral CBD Bioaccessibility

Oral means to consume something through your mouth. In terms of CBD, common oral consumption methods include CBD capsules, CBD edibles, and CBD beverages.

While oral consumption methods do offer certain benefits, any substance consumed will have to pass through our metabolic and digestive systems, which will filter out a large portion of the CBD, drastically reducing its bioavailability. The most optimistic study finding on bioavailability is about 20%. To give you a clear picture, if you eat an edible that contains 100mg of CBD, approximately 20mg will actually reach your bloodstream.

Sublingual CBD Bioaccessibility

Under the tongue, there is a vein called the sublingual gland. When a substance is administered to the sublingual gland, it gets absorbed directly into the bloodstream, which is referred to as sublingual consumption or sublingual administration. Common sublingual consumption methods include CBD tinctures, CBD lozenges, and CBD sprays.

Sublingual consumption is more direct and it impacts the body quicker than oral consumption and maintains higher bioavailability, only being degraded from enzymes in the mouths saliva.

Because there are a few different factors that will impact the bioavailability of sublingual consumption (most involving the quality of CBD), reported rates range from 12%-35%, which is higher than oral consumption.

Vaporized CBD Bioaccessibility

Vaping involves inhaling CBD directly into the lungs, typically through a vape pen or vaporizer device. By directly entering the lungs, the CBD can then quickly and directly enter the bloodstream, with decreased breakdown rates and higher CBD bioavailability.

With numerous medical studies reporting bioavailability rates between 34–46%, and some even reporting up to 56%, vaporizing CBD is by far one of the most effective methods to take CBD.

By understanding how bioavailability works, it not only helps you increase the effectiveness of the CBD you’re taking because you will understand how to adjust the dose base on the method of consumption. Most folks opt for capsules or edibles based on ease and convenience. You can use the products anywhere, anytime, and no one around you will be any wiser. By understanding how these methods differ with bioavailability, you can now understand how to adjust your dose to get the desired effects.

CBD Bioavailability

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New Rules for CBD Products in Florida

New Rules for CBD Products in Florida

New Rules for CBD Products in Florida

As sales boom in retail establishments throughout Florida, state regulators are now keeping tabs on CBD products that marketers claim can ease arthritis, anxiety, sleeplessness, and much more.

CBD products including gummy bears, chocolates and dog treats — are part of a national mania for CBD, a non-euphoric compound derived from cannabis plants.

CBD products have been sold for years without any governmental oversight in Florida, until January 2020. That’s when Agriculture Commissioner Nikki Fried’s office took charge of CBD-based products consumed by people and pets, as new rules went into effect on Jan. 1, 2020.

In 2018, Congress passed a law that took hemp — defined as cannabis that has less than 0.3 percent of euphoria-inducing THC — off the list of controlled substances and gave states the authority to regulate hemp and related products. Florida lawmakers during the 2019 legislative session put Fried’s office in charge of establishing the regulatory structure for hemp, along with products containing CBD being sold at gas stations, grocery stores, and flea markets.

New Rules for CBD Products in Florida – The landscape shifted in Florida’s CBD world the day the new rules went into effect. Until recently, as demand for CBD products skyrocketed, Florida’s attorney general, agriculture commissioner, and health officials — as well as most law enforcement entities — insisted the non-euphoric cannabis products existed in a legal “gray area” that none of the regulators had the authority to police. That’s no longer the case.

“Prior to these rules being adopted and taking effect, we didn’t have regulatory authority. Now we do, and we have that up and going so that we can make sure consumers are protected,” Fried’s cannabis director, Holly Bell, told The News Service of Florida.

Fried’s inspectors have fanned out across the state to make sure retailers are complying with the new rules, which address issues such as pesticides, how packages are labeled and the inspection of products sold or produced in the state. The hemp rules include “ingestion,” or “the process of taking food into the body through the gastrointestinal tract through eating or drinking.”

“[Inspectors] are going out, looking at what’s on the shelf and if you are not compliant with those labeling laws, you will be given a certain amount of time to become compliant,” Bell said.

Retailers, who now have to pay Fried’s department $650 to sell products with CBD, will have between 30 and 45 days to comply with the law, Bell said.

Some retailers are embracing the new regulations. Ashley Guy, the owner of Tallahassee-based Tallulah CBD + Juice Bar, told the News Service that eight regulators recently visited her store to conduct a training. While the inspectors were there, a customer who had purchased an item from another store came in, Guy said. The item, which had no expiration date and was more expensive than a similar item that Guy had on her shelves, “was really sketchy,” she said. Guy said she welcomes the new rules because they could help ensure consumers’ safety by ridding the market of unregulated retail products. “I hope they do yank them too because there are a lot of really bad products out there,” she said. “You don’t know where the CBD’s coming from. It could be China. It could be junk. … We don’t even know. If you’re putting something in your body, it should be a good product.”

But some retailers aren’t as prepared. Some vendors with a smaller inventory “may find it challenging” to discard items that aren’t in compliance with new packaging requirements, according to lobbyist Jeff Sharkey, who represents the Florida Hemp Industries Association. “The question’s going to be whether or not there’s going to be any enforcement or inspection of that inventory,” Sharkey said in an interview. The new regulations will require “a tremendous amount of education” for retailers, producers, and consumers, he added. “This is a whole major industry that’s now coming online in Florida. It’s a big state. And CBD is very popular. So yeah, it will take a major effort from not only from the Florida Department of Agriculture and Consumer Services, but a lot of people in this industry,” Sharkey said. Article from Sun-Sentinal Here.

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CBD for Travel Anxiety

CBD for Travel Anxiety

CBD for Travel Anxiety

CBD for Travel Anxiety

How CBD Can Help Ease Your Stress So You Can Travel Comfortably

Fighting traffic on your way to the airport, checking your watch to make sure you arrive in time to get your boarding pass and check your bags, standing in line of impatient travelers as you slowly make your way through security; it all contributes to making the experience of flying way more stressful than it needs to be. Not to mention the biggest concern of them all – actually getting on an airplane and flying through the sky. 

According to some estimates, as many as 25% of all Americans suffer some form of nervousness or anxiety about flying. We can’t recommend anything to get rid of the traffic, security, or the occasional delay or canceled flight, but we can strongly recommend something to help put your mind at ease while you prepare to embark on your flight.

CBD has been used successfully to treat anxiety and depression in individuals suffering from social anxiety, post-traumatic stress disorder, obsessive-compulsive disorder, and other forms of anxiety. But can you use CBD for travel anxiety and help you relax on your flight?

There are no conclusive studies to determine the effectiveness of CBD for travel anxiety, but with overwhelmingly positive results associated with CBD and other forms of anxiety, the association seems logical.

Traveling, especially flying, can cause you to be irritable and on edge. Thankfully, your endocannabinoid system (ECS) has receptors in the brain that help to elevate your mood and promote a sense of calm. Activating those receptors by taking CBD may help take the edge off and potentially reduce irritability.

Relaxing can also be a challenge when you travel. The stress of getting to the airport on time, taking off from the runway, and being sedentary in an uncomfortable seat for hours can be a nerve-racking experience for many travelers. CBD’s interaction with your ECS can cause the body to relax enough to ease into a more restful state and maybe even help you find sleep during your flight.

Best CBD Products For Travel

The legalization of hemp-derived CBD products has made it easier than ever to travel with this powerful organic remedy. In fact, in some US cities, you can even purchase CBD products before your flight at the airport. Although CBD itself is legal and completely safe to fly with, make sure the container size is TSA approved before tossing it in your carry-on bag.

There are several CBD options available to travelers suffering from flight anxiety, but we recommend choosing an edible like gummies to avoid unwanted looks from other passengers.

For longer trips, apply a CBD transdermal patch to feel a more sustained delivery of tranquility as you fly. If you normally take CBD oil in a traditional tincture, consider taking your dose within an hour of your flight. This way the effects of the CBD oil should kick in right around the time of take-off and hopefully last for the duration of your flight.

Lastly, the physical stress from sitting can cause poor circulation in your legs, discomfort, and soreness in your body. Consider a CBD topical to help with neck, back or leg pains. Topical roll-ons are a good choice. They can be easily brought in your carry on and applied even while in flight.

Next time you fly, consider trying CBD to make flying enjoyable and anxiety-free. READ ORIGINAL

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Researcher Hopes Discovery Not Overlooked

Researcher Hopes Discovery Not Overlooked

Researcher Hopes Discovery Not Overlooked

Cannabis Research Pioneer – Researcher Hopes Discovery Not Overlooked

Decades after Raphael Mechoulam linked CBD with treating epilepsy, his latest finding may help develop new drugs for psoriasis, arthritis, and anxiety.

Raphael Mechoulam, an Israeli organic chemist and professor of medicinal chemistry at the Hebrew University of Jerusalem, remembers the letdown after his groundbreaking discoveries surrounding the structure of the cannabis compounds CBD and THC in 1963 and 1964, followed by clinical tests with CBD published in 1980.

“Not much happened,” Mechoulam said, noting that it would take more than 30 years before his clinical work on using CBD, or cannabidiol, to treat epilepsy became widely accepted. Greenwich Biosciences, which is owned by GW Pharmaceuticals, was able to develop the first cannabis-derived drug that built on Mechoulam’s research. The drug, Epidiolex, treats seizures associated with two rare forms of epilepsy and was approved by the FDA only last year. (2018)

But even as his work laid the foundation for the modern cannabis industry and for understanding how cannabis interacts with the human body, a white whale eluded research: cannabis acids, which are compounds that are produced in the plant when it is alive and may be more potent than their better-known derivatives, such as CBD and THC.

That changed in September 2019, when Mechoulam and a group of researchers announced at a medical cannabis conference in Pasadena, California, that they have developed a process for creating synthetic, stable acids that are found within the plant, and that the synthetic acids, which include acid versions of CBD and THC, are now available for licensing to companies for drug development.

The discovery paves the way for drug companies to potentially develop new drugs based on the acids for a variety of health issues such as psoriasis, arthritis, anxiety and inflammatory bowel disease.

In a 2018 British Journal of Pharmacology study, Mechoulam and his co-authors wrote that their synthetic compound, cannabidiolic acid methyl ester (called HU-580 in the paper) could be more effective than existing CBD remedies, making it “a potential medicine for treating some nausea and anxiety disorders.” Those initial clinical tests found the acids have yielded results on par, and even exceeding, existing treatments, without the side effects.

The naturally occurring but unstable CBD acid (CBDA) is a thousand times more potent than CBD in binding to a particular serotonin receptor thought to be responsible for alleviating nausea and anxiety.

“It’s an interesting molecule that potentially doesn’t have side effects,” said Dan Peer, managing director of the Center for Translational Medicine and head of the Cancer Biology Research Center at Tel Aviv University.

“It works like a steroid. If it doesn’t have adverse effects, then you have a replacement, which is great,” Peer said, discussing testing he did with cannabis acids and inflammatory bowel disease.

Ziva Cooper, research director of the UCLA Cannabis Research Initiative, said EPM’s research confirms what many in the field have long suspected about cannabis acids, but have been unable to confirm due to their instability.

“Their work is quite innovative, and it definitely builds on what we know related to the potential therapeutic effects of cannabinoids,” Cooper said, adding that the compound could be particularly effective for pain control. Cooper said that while more testing will be needed to determine effectiveness and safety for humans, EPM’s results so far are “quite encouraging.”

As the U.S. government plans to spend $3 million to research CBD, pharmaceutical industry veterans still urge caution, while lending some insight regarding why more drugs have not been built on cannabis compounds.

“The drugs that are produced are just not potent enough,” said Peer, referring to the CBD, THC, and other nonacids.

These factors, in addition to social mores, have all led to a situation where pharmaceutical companies have not been a major presence in cannabis development. READ ORIGINAL

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CBD FAQ’s

CBD FAQ's

CBD FAQ’s

The CBD FAQ’s

Everything you wanted to know about CBD.

First things first. What exactly is CBD? – CBD FAQ’s #1

CBD is an abbreviation for cannabidiol, a chemical compound found in the cannabis plant. CBD is one of more than 100 identified cannabinoids. In recent years, it has been promoted as a treatment for a wide range of health concerns, including anxiety, chronic pain, insomnia, seizures, and more.

Does CBD Come From Marijuana? – CBD FAQ’s #2

CBD is derived from what is known as industrial hemp, which is a relative of marijuana. Scientifically speaking, both industrial hemp and marijuana are classified as strains of Cannabis Sativa. While the two kinds of cannabis may look alike – chemically they are different. Industrial hemp contains a lot of CBD but very little THC (tetrahydrocannabinol), the active ingredient in recreational and medical marijuana.

So CBD Get Me High? – CBD FAQ’s #3

No, it won’t. While marijuana does contain CBD, it’s the THC that gives that kind of cannabis its psychoactive high. Because it has such a negligible amount of THC, consuming – even smoking – CBD won’t get you high. In fact, CBD can actually inhibit the impact of THC.

Why Is CBD Everywhere Nowadays? – CBD FAQ’s 4

Laws and regulations governing cannabis have been in flux at the federal and state levels. CBD possession is now legal in many states. Since then, CBD products have appeared on store shelves and a growing number of farmers have cultivated cannabis for a variety of commercial purposes, including CBD production and use for fiber and food.

Why Do People use CBD? – CBD FAQ’s #5

According to Dr. Rachna Patel, author of “The CBD Oil Solution,” CBD “has been shown to reduce inflammation, intercept pain signals to the brain, boost serotonin levels, dampen the flight-or-fight response, and help regulate sleep.” CBD has been promoted as an alternative therapy for a variety of ailments, including chronic pain, anxiety, insomnia, migraines, menstrual cramps, post-traumatic stress disorder, neuropathy, Parkinson’s disease, multiple sclerosis, and more. For such uses, it is sold as a dietary supplement, not a prescription medicine, so it is not regulated by the U.S. Food and Drug Administration.

The only FDA-approved medical use of CBD is a pharmaceutical drug called Epidiolex, which was created in 2018 to treat two severe forms of epilepsy. Research is ongoing about the medical effects of CBD. According to Dr. Peter Grindspoon of Harvard Medical School, a study found that “CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.”

How Does CBD work? – CBD FAQ’s #6

CDB interacts with what is called the endocannabinoid system within our bodies. This system can impact our mood, memory, appetite, perception of pain, and more, and it is impacted by substances both produced inside our bodies and outside them (such as CBD and THC). THC fits snugly into certain cannabinoid receptors, causing the brain to release dopamine, which causes a high. CBD molecules also fit into the same receptors, but not in the same way as THC. This causes particular chemical reactions in the body, but not a THC-driven high.

Is CBD Addictive? – CBD FAQ #7

According to a 2017 report by the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential. … To date, there is no evidence of public health-related problems associated with the use of pure CBD.”

Can CBD Have Side Effects? – CBD FAQ’s #8

“Side effects of CBD include nausea, fatigue, and irritability. CBD can increase the level of the blood thinner coumadin in your blood, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does,” writes Dr. Peter Grindspoon of Harvard Medical School. CBD can also impact the metabolism of some chemotherapy treatments, according to Dr. Brent Bauer, director of the Mayo Clinic Integrative Medicine and Health Research Program. Bauer advises that people talk to their health care providers about using CBD.

What Kind of Products Can I Find CBD In? – CBD FAQ #9

CBD is available in a myriad of over-the-counter products. Most commonly, it’s sold as an oil, which is extracted from the cannabis plant and tested to ensure its THC content is below 0.3%. This oil can be added to topical creams and salves, gummies, bath bombs, breath sprays, inhalable items, and more!

Who Grows CBD-Producing Hemp? – CBD FAQ #10

An increasing number of farmers. There are thousands of registered growers in the United States, but only a fraction of them actually plant industrial hemp. Last year, there was an increase in growers of more than 500%. Those farmers grew thousands of acres of industrial hemp.

What Else Can Industrial Hemp Be Used For? – CBD FAQ’s #11

Hemp has a myriad of uses. According to a 2018 report by Congressional Research Services, there are an estimated 25,000 products derived from hemp in nine categories: agriculture, textiles, recycling, automotive, furniture, food and beverages, paper, construction materials, and personal care. You can find hemp in everything from twine, diapers, and fiberboard to salad oil, bird seed, animal bedding, and shampoo.

READ ORIGINAL ARTICLE

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Should You Use CBD?

Should You Use CBD?

Should You Use CBD?

Proponents claim CBD can help ease pain, anxiety, depression, and stress, boost focus and productivity, improve the immune system, reduce inflammation and more. And – unlike its psychoactive cousin THC – CBD, they say, is harmless, legal and can’t get you high. “The known is it’s good for you, it helps a lot of people and a lot of things, and you can’t hurt yourself,” says Phil Asquith, a farmer and producer of extra-virgin olive oil in California, who founded one of the first companies in the CBD space. “The unknown is all the details.”

Should You Use CBD? – The Science

At least one benefit of CBD is well-supported by science: It can be effective in treating children with rare, genetic seizure disorders. Adults, children and even animals with epilepsy have been shown to benefit from the chemical too, the World Health Organization reports. There’s also some evidence that CBD can help with anxiety, says Dr. Robert Carson, an assistant professor of neurology and pediatrics at Vanderbilt University who focuses on children with epilepsy. “In children, especially those with autism spectrum disorders, this may manifest as improved interactions with others,” he says. Other preliminary research shows CBD holds promise for conditions including Alzheimer’s disease, cancer, psychosis, and Parkinson’s disease – and is pretty much impossible to abuse or become addicted to, WHO says.

“If it proved effective for anxiety, depression and panic disorder, it may have other effects as well that could be useful and beneficial [but] this is a really early stage,” says David Shurtleff, the acting director of the National Center for Complementary and Integrative Health. His organization’s stance: “Take it one step at a time and do the work and really state where we are right now with the research,” he says.

What’s there to lose?

So, many of CBD’s popularized benefits aren’t well-proven. But are there any harms in trying CBD-containing products? In a word, yes. While any reported side effects from CBD alone are minor (think dry mouth and dizziness), they can be serious if the CBD products interact with other medications, experts say. Since CBD is metabolized by the same enzyme in the liver that metabolizes many conventional medicines and supplements, the chemical can cause the levels of other drugs in the system to rise; in some cases – like for those taking a drug to prevent their bodies from rejecting a donor organ – to a deadly level, Tishler says.

“Please be open with [your] physicians regarding what [you] are taking,” says Carson, who also worries about patients who turn to CBD products instead of well-proven treatments for conditions like depression.

Keep in mind, too, that CBD product companies use different CBD sources, extraction methods and production techniques – and not all resulting products are created equal. You’ll have to do your own research to determine which companies you’re willing to trust. READ MORE.

Mind and Body Improvements CBD Quality Commitment

At Mind and Body Improvements, we go above and beyond to bring you the highest quality CBD Symptom Relief products so that you can start your journey to a better life. We are adding products daily to our large selection of amazing products that you are sure to love and enjoy. We partner with industry experts to elevate our service and product offerings for you. If you ever have any questions, we want to hear from you. Please feel free to fill out the contact form on this page today. Our customers are VERY IMPORTANT to us and we make it a point to get back to every inquiry in a timely manner.

CBD is not marijuana and does not contain enough THC to be detectable or to feel any euphoric effects. If you are interested in learning about Medical Marijuana, please visit our valued partner CalmEffect. They have all the answers you need for those interested in higher-level THC content options.

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Baby Treated with CBD

Baby Treated with CBD

Baby Treated with CBD

In December 2016, Nicole and Ernie Nunez brought their beautiful baby girl, Amylea, into the world. However, when they brought her home, things quickly took a turn for the worst.

“About a day after we went home from delivery is when she had her first seizure,” Nicole said. “She has a rare form of epilepsy. They don’t know exactly the type.”

For two months, the Nunez family had been desperately trying to treat their daughter’s condition. Doctors in Albuquerque, New Mexico, where the family is from, were unable to find a cause and unable to treat young Amylea. So, the family fled to Colorado.

At the Children’s Hospital in Aurora, doctors continued a drug cocktail in an attempt to stop the horrible seizures, but these medications were not without side-effects.

“The medication was hard for her liver, and so we were trying to do something different that’s not so bad on her body,” Ernie said, explaining why the couple decided to use cannabis oil.

When the family heard about the seemingly miraculous effects of the cannabis oil known as Charlotte’s Web, they became hopeful and set out to get it for their daughter.

Charlotte’s Web is a strain of cannabis named after a young girl, Charlotte Figi, whose life it quite literally saved. Charlotte had her first seizure when she was three months old. Over the next few months, she had frequent seizures lasting two to four hours, and she was hospitalized repeatedly.

But her parents found a strain of cannabis that turned their daughter’s suffering completely around. Since then, countless other children have had their lives saved by this amazing plant.

“For us to get the approval for us to administer it while she was in the NICU while she was a patient…it’s kind of like a miracle,” Nicole said. “Because they were completely against it saying, ‘No you can’t do it, you have to wait until she’s an out-patient.”

Even though the doctors gave the approval to treat Amylea with the oil, they won’t administer it to her, so the family has done it themselves. She became the first Baby Treated with CBD in a hospital.

After only a handful of doses, her parents said the nurses noticed a positive change.

According to the family, Amylea is the first and youngest patient to ever receive cannabis oil as a treatment in a hospital.

The significance of cannabis oil being used to treat an infant in a hospital should not be overlooked. What this move effectively illustrates is that cannabis is a viable medical option, and any classification by the federal government as a Schedule 1 drug is as absurd as it is immoral.

The Free Thought Project recently reported on the findings of a study that showed cannabis oil to be a highly effective treatment for intractable epilepsy.

Of 261 patients given CBD treatment, 45% experienced a significant reduction in seizure frequency, and 9% were seizure-free at three months. Some children continued to experience benefits after the trial ended, even one year after.

Read the original Baby Treated with CBD article HERE.

Want more information on what CBD is? CLICK HERE

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CBD and Cancer Treatment

CBD and Cancer Treatment

CBD and Cancer Treatment

A review concluded that “preclinical studies, particularly recent ones, including numerous animal models of tumors, unanimously suggest the therapeutic efficacy of CBD” and that “CBD may potentially play a role in the palliative care of patients, especially concerning symptoms such as pain, insomnia, anxiety, and depression.” This data on CBD and Cancer Treatment may bring about an entirely new way to treat cancer and bring much-needed relief to those suffering through traditional cancer treatments. Tumor-inhibition could be an amazing link to recovery.

BACKGROUND:
Cannabis was used for cancer patients as early as about 2500 years ago. Experimental studies demonstrated tumor-inhibiting activities of various cannabinoids more than 40 years ago. In view of the status of tetrahydrocannabinol (THC) as a regulated substance, non-psychotomimetic cannabidiol (CBD) is of particular importance.

OBJECTIVES:
Efficacy of pure CBD in various animal models as well as initial results (case reports) from patients.

METHODS:
Review of the literature on animal experiments and observations in humans.

RESULTS:
Preclinical studies, particularly recent ones, including numerous animal models of tumors, unanimously suggest the therapeutic efficacy of CBD. In isolated combination studies, synergistic effects were generally observed. In addition, CBD may potentially play a role in the palliative care of patients, especially concerning symptoms such as pain, insomnia, anxiety, and depression. Further human studies are warranted. READ FULL REPORT

Learn more about what CBD Oil is HERE.

Mind and Body Improvements CBD Quality Commitment

At Mind and Body Improvements, we go above and beyond to bring you the highest quality CBD Symptom Relief products so that you can start your journey to a better life. We are adding products daily to our large selection of amazing products that you are sure to love and enjoy. We partner with industry experts to elevate our service and product offerings for you. If you ever have any questions, we want to hear from you.

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Study – CBD Could Treat Addiction to Opioids

Study Finds CBD Could Effectively Treat Addiction to Opioid Drugs

Study Finds CBD Could Effectively Treat Addiction to Opioid Drugs

A study states that CBD may effectively treat heroin addiction. It’s the first study of its kind showing that the plant’s constituents could curb cravings for opioid drugs like heroin.

Study Finds CBD Could Effectively Treat Addiction to Opioid Drugs

A small study has offered new data on how cannabis-derived cannabidiol (CBD) could help to curb the international opioid crisis.

Results of the study published in May 2019, in the American Journal of Psychiatry, suggest that CBD could help to reduce the anxiety and cravings experienced by patients recovering from heroin addiction. Researchers reported that CBD may help to dampen signals in the body that trigger cravings and anxiety in former opioid abusers, in addition to lowering patients’ heart rates and levels of stress hormones.

Conducted at Mount Sinai hospital in New York, the double-blind, randomized, controlled study looked at 42 people with a heroin-use disorder who were abstaining from the drug at the time. Participants took either a placebo, a 400 milligram dose of CBD, or an 800 milligram dose at different intervals, allowing researchers to examine the short- and long-term effects of administered CBD. During the study sessions, researchers alternately monitored participants’ vital signs such as heart rate, blood pressure, respiratory rate, and oxygen saturation.

Researchers found that patients who were given CBD exhibited lowered feelings of anxiety or craving when exposed to certain psychological cues, such as videos of drug paraphernalia. Tests of such participants’ saliva also showed lowered levels of stress hormones, and participants’ heart rates were found to be lower than those in the placebo group. Some of these effects were evident in patients up to a week after their final dose of CBD. 

Neuroscientist Yasmin Hurd, the study’s first author and director of the Addiction Institute at the Icahn School of Medicine at Mount Sinai, commented in a statement that the results are a further indication that CBD should be considered as a potentially significant option for treating patients recovering from opioid abuse.

“To address the critical need for new treatment options for the millions of people and families who are being devastated by this epidemic, we initiated a study to assess the potential of a nonintoxicating cannabinoid on craving and anxiety in heroin-addicted individuals,” Hurd wrote. “The specific effects of CBD on cue-induced drug craving and anxiety are particularly important in the development of addiction therapeutics because environmental cues are one of the strongest triggers for relapse and continued drug use.”

Hurd also noted that the cannabinoid chemical’s anxiety-reducing capability extends to other kinds of patients, but could offer key relief for patients recovering from opioid dependence. “[This] particular anxiety leads someone to take a drug that can cause them death, and anything we can do to decrease that means increasing the precious chance of preventing relapse and saving their lives.”

In recent years, CBD has been popularly treated as a potential “miracle drug,” in large part because of its ability to stimulate the endocannabinoid system, which maintains balance and function in the body. When this system itself gets out of balance, introducing phytocannabinoids such as cannabis-derived CBD can help to re-balance that system, allowing it to get back to work throughout the body.

It’s also worth noting that subjects in the Mount Sinai study were administered fairly large doses of CBD, which could have cost as much as $50 in the current medical cannabis market, based on typical per-milligram prices. Everyday sufferers of anxiety, pain, and more serious illnesses may use anywhere between 5 and 200 milligrams per day, and numerous researchers believe that in some patients, a lower dose of cannabidiol may be more efficacious than a higher one.

As NBC News reported, Hurd and her team previously studied the effects of CBD and opioid abuse in animals, and after observing a reduced tendency to use heroin in those subjects, they decided to extend their research to human groups.

To stay up-to-date on all new developments in the CBD world, please visit our contact page and fill out our contact form. You may also ask any questions should you have any.

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CBD Oil for Anxiety

CBD Oil for Anxiety

CBD Oil for Anxiety

CBD oil interacts with different parts of the nervous system as well as the endocannabinoid system. Learn how CBD oil for anxiety has helped others cope and what CBD oil products may be right for you.

Millions of Americans suffer from Generalized Anxiety Disorder or (GAD). Every year, thousands of prescriptions are given out by health care professionals to help patients overcome severe anxiety and depression.

GAD

In order to live a normal life in society, people have resorted to taking drugs such as Benzodiazepines and Selective Serotonin Reuptake Inhibitors, also known as SSRIs. Studies show that these drugs can have serious long term side effects and strong interactions with alcohol and other drugs that can negatively affect one’s health.

People with anxiety oftentimes feel the negative side effects of these drugs and look to cannabis for a safer alternative. A glass of wine taken with a prescription anxiety drug as an example could easily double the cognitive ability of the pills in a negative way.

Over-the-counter CBD is used by thousands if not millions of people around the world to improve overall health and specifically with anxiety issues.  And CBD oil side effects are almost non-existent.

Because our bodies respond more efficiently to mental health issues when we are in a state of homeostasis, the endocannabinoid system plays an important role when it comes to anxiety issues.

CBD Oil for Anxiety

CBD and Anxiety: What Does Science Tell Us?

Studies show that cannabis works with both the CB1 and CB2 receptors in the human body. The CB1 receptors help to regulate our emotional well being as well as regulation of homeostasis and even help with general pain.

GAD

Since CBD is a phytocannabinoid; meaning it is an external source of cannabinoids, it can help balance the health of our endocannabinoid system. Our endocannabinoid system is comprised of cannabinoids created naturally by our bodies. When you think of endo you can think of internal. External sources such as CBD can help to balance this system.

Also, a study showed that endocannabinoid 2-AG could potentially be responsible for the regulation of our mental clarity. When CBD and other cannabinoids are introduced into the system via inhalation or orally, some patients report strong anxiety reduction.

CBD oil can help interact with various systems in our body in efforts to help bring us to a state of homeostasis and better brain health. Because CBD does not have the strong psychoactive effects that THC can have on the mind, many people feel more comfortable when taking CBD for anxiety.

CBD products over the counter are not allowed to be sold with more than .03% THC. This is a very low amount of it and typically not even enough for the consumer to feel the mental effects.

Introducing cannabinoids from external sources, in a new study that scientists have found patients reporting therapeutic value when it comes to anxiety and a number of other brain-related issues.

The central nervous system helps our mind reduce anxiety and gain clarity. The endocannabinoid system interacts with the central nervous system as well.

CBD Products for Anxiety 

Since everyone is different, one glove doesn’t fit all when it comes to anxiety. Generalized anxiety disorder can have very serious problems in day to day life functioning. Adults with kids are especially prone to anxiety since they have so many people to watch and keep healthy.

It is important to note here that the FDA has warned companies about claiming that CBD products can help treat an illness, such as GAD or Alzheimer’s. We are not suggesting that CBD be used to replace a doctor-prescribed medication. Always seek the advice of a medical professional.

Edibles for Anxiety

Some people enjoy the ease of taking edible CBD products such as gummies or candy. The sugary flavor of the gummies are generally liked by most people and it is easy to know exactly how much CBD you are getting in each dose. During a panic attack, it can be difficult to measure something correctly. Popping a few gummy bears in your mouth can be a simple way to give you the CBD you need.

CBD Oil for Anxiety

The only problem with taking CBD in edible form is the fact that it will generally take longer to hit your system with more serotonin. The candy goes straight to the stomach rather than directly into the bloodstream.

When you are taking something that sits in the belly, it can also absorb into the food you already have inside. After finishing a large meal with meat and carbs such as bread, you may notice the edible you take right after does not give you any results for a long time.

If you are on an empty stomach, you might find the edible taking effect a lot sooner. 

Tinctures for Anxiety

CBD Tinctures on the other hand, when taken sublingually, may take effect much sooner than pills or candy. Sublingual administration is the application of medicine in the mouth under the tongue. The medication is absorbed through the light tissue under the muscle and proceeds to enter the bloodstream. 

CBD can be administered through the sides of the cheek as well, but right under the tongue has shown to absorb and deliver serotonin faster.

CBD Oil for Anxiety

Since CBD tinctures can be very costly, we suggest trying before buying. Most companies have smaller versions of their most popular tinctures.

Final Thoughts on CBD Oil for Anxiety

There have been many studies conducted that show that introducing CBD Oil for Anxiety (phytocannabinoids) into our systems has shown to greatly affect the way we function in our day to day lives and improve our health.

CBD is a great option for people with anxiety disorders because it has shown to have much fewer side effects than many of the prescription medications.

CBD has helped many people cope with anxiety issues.  That said, always, always seek medical advice from a medical professional if you are suffering from GAD.

The endocannabinoid system we have in our bodies produce cannabinoids to regulate our moods. CBD can simply change the mindset just enough that you are able to go about your day happy.

Remember, CBD oil products have not been approved by the FDA in treating a disease so remember, if you are suffering from GAD, it is important to always consult the advice of a medical professional.